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AKT inhibitor
CAS No. 1004990-28-6
AKT inhibitor ( AKT protein kinase inhibitor )
Catalog No. M10037 CAS No. 1004990-28-6
A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 215 | In Stock |
|
| 10MG | 309 | In Stock |
|
| 25MG | 521 | In Stock |
|
| 50MG | 746 | In Stock |
|
| 100MG | 1035 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAKT inhibitor
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NoteResearch use only, not for human use.
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Brief DescriptionA broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay).
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DescriptionA broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay); shows >900-fold selectivity over PKA; excellent PK profiles and effective in in vivo models of xenograft tumor.
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SynonymsAKT protein kinase inhibitor
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorAkt
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1004990-28-6
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Formula Weight400.43
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Molecular FormulaC20H22F2N6O
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NC[C@]1(N)CN(C2=C3C(NC=C3CC)=NC=N2)CC1)C4=CC=C(F)C=C4F
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Chemical NameBenzamide, N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-pyrrolidinyl]methyl]-2,4-difluoro-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Freeman-Cook KD, et al. J Med Chem. 2010 Jun 24;53(12):4615-22.
2. Chen SF, et al. J Mol Model. 2013 Nov;19(11):5097-112.
2. Chen SF, et al. J Mol Model. 2013 Nov;19(11):5097-112.
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